Human FCRL5 Protein, His Tag

The protein has a predicted molecular mass of 92.1 kDa after removal of the signal peptide. The apparent molecular mass of FCRL5-His is approximately 100-130 kDa due to glycosylation. This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.