Recombinant human NRG1 protein with C-terminal human Fc tag
Expression Host : HEK293 The protein has a predicted molecular mass of 50.05 kDa after removal of the signal peptide. The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD) .
Product Specifications
Product Name Alternative
ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; NRG1-IT2; SMDF
Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Shipping Conditions
Delivery in 1-2 weeks
Storage Conditions
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
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MED30, ID (MED30, THRAP6, TRAP25, Mediator of RNA polymerase II transcription subunit 30, Mediator complex subunit 30, TRAP/Mediator complex component TRAP25, Thyroid hormone receptor-associated protein 6, Thyroid hormone receptor-associated protein compl
