Recombinant human CD6 protein with C-terminal human Fc tag

Expression Host : HEK293 The protein has a predicted molecular mass of 67.87 kDa after removal of the signal peptide. This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685) . Multiple transcript variants encoding different isoforms have been found for this gene.