Recombinant human MERTK protein with C-terminal human Fc tag
Expression Host : HEK293 The protein has a predicted molecular mass of 78.8 kDa after removal of the signal peptide. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .
Product Specifications
Product Name Alternative
C-Eyk; c-mer; MER; RP38; Tyro12
Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Shipping Conditions
Delivery in 4-6 weeks
Storage Conditions
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Frequently Asked Questions
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