Recombinant human IL9R protein with C-terminal human Fc tag
Expression Host : HEK293 The protein has a predicted molecular mass of 60.83 kDa after removal of the signal peptide. The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9) . The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.
Product Specifications
Product Name Alternative
CD129, IL-9R
Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Shipping Conditions
Delivery in 4-6 weeks
Storage Conditions
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
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