Recombinant human IL1R3 protein with C-terminal human Fc tag

Expression Host : HEK293 The protein has a predicted molecular mass of 73.7 kDa after removal of the signal peptide. This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.