Recombinant human MST1R protein with C-terminal human Fc tag
Expression Host : HEK293 The protein has a predicted molecular mass of 128.15 kDa after removal of the signal peptide. This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.
Product Specifications
Product Name Alternative
CD136; CDw136; NPCA3; PTK8; RON
Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Shipping Conditions
Delivery in 4-6 weeks
Storage Conditions
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
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