Recombinant Human IL13RA1 Protein with C-terminal6Ã-His tag

Expression Host : HEK293 The protein has a predicted molecular mass of 37.7 kDa after removal of the signal peptide.The apparent molecular mass of IL13RA1-His is approximately 55-70 kDa due to glycosylation. The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.