Recombinant Human ROR1 Protein with C-terminal6Ã-His tag
Expression Host : HEK293 The protein has a predicted molecular mass of 42.8 kDa after removal of the signal peptide. The apparent molecular mass of ROR1-His is approximately 55-70 kDa due to glycosylation. This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Specifications
Product Name Alternative
ROR1, NTRKR1
Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
Shipping Conditions
Delivery in 1-2 weeks
Storage Conditions
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
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