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Recombinant human TIGIT Protein with C-His tag

Expression Host : HEK293 The protein has a predicted molecular mass of 13.85 kDa after removal of the signal peptide.The apparent molecular mass of TIGIT-His is approximately 17-25 kDa due to glycosylation. This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH) . The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.

Product Specifications

Product Name Alternative

TIGIT, VSIG9, VSTM3

Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Shipping Conditions

Delivery in 1-2 weeks

Storage Conditions

Store at -80°C for 12 months (Avoid repeated freezing and thawing)

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