Recombinant human TNFRSF10B protein with C-terminal Mouse Fc tag
Expression Host : HEK293 The protein has a predicted molecular mass of 40.5 kDa after removal of the signal peptide. The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Product Specifications
Product Name Alternative
TNFRSF10B, TRAILR2, TRAIL-R2, CD262, DR5, KILLER, TRICK2, ZTNFR9, TRICKB
Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Shipping Conditions
Delivery in 1-2 weeks
Storage Conditions
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
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