Recombinant human PD-1 protein with C-terminal6Ã-His tag
Expression Host : HEK293 The protein has a predicted molecular mass of 16.8 kDa after removal of the signal peptide. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Product Specifications
Product Name Alternative
PDCD1, PD1, CD279, SLEB2
Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Shipping Conditions
Delivery in 1-2 weeks
Storage Conditions
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Frequently Asked Questions
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