Recombinant Human SIGLEC10 protein with C-terminal6Ã-His tag

Expression Host : HEK293 The protein has a predicted molecular mass of 59.0 kDa after removal of the signal peptide.The apparent molecular mass of SIGLEC10-His is approximately 70-100 kDa due to glycosylation. SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405) .