SAE1/SAE2 Human
Source:Sf9 insect cells.Physical Appearance:Sterile Filtered colorless solution.Biological ActivitynullSAE1 and SAE2 form heterodimers which take part in the posttranslational modification of proteins (sumoylation) . This process regulates protein structure as well as intracellular localization of the target. SAE1/SAE2 may indicate on dermatomyositis (DM) as autoantibodies against those 2 proteins have been found in patients.SAE1/SAE2 Human Recombinant produced in SF9 is glycosylated, polypeptide chain containing 2 subunits (SAE1 subunit molecular mass is 39kDa & SAE2 subunit molecular mass is 73kDa) . The subunits associate to form a complex.The SAE1/SAE2 is expressed with a -10xHis tag and purified by proprietary chromatographic techniques.
Product Specifications
Purification
Greater than 80.0% as determined by SDS-PAGE.
Format
SAE1/SAE2 is supplied in 20mM HEPES buffer pH-7.5, 400mM NaCl and 20% glycerol.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
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