SAE1/SAE2 Human

Source:Sf9 insect cells.Physical Appearance:Sterile Filtered colorless solution.Biological ActivitynullSAE1 and SAE2 form heterodimers which take part in the posttranslational modification of proteins (sumoylation) . This process regulates protein structure as well as intracellular localization of the target. SAE1/SAE2 may indicate on dermatomyositis (DM) as autoantibodies against those 2 proteins have been found in patients.SAE1/SAE2 Human Recombinant produced in SF9 is glycosylated, polypeptide chain containing 2 subunits (SAE1 subunit molecular mass is 39kDa & SAE2 subunit molecular mass is 73kDa) . The subunits associate to form a complex.The SAE1/SAE2 is expressed with a -10xHis tag and purified by proprietary chromatographic techniques.