KLRB1 Human, Sf9

Source: Sf9, Baculovirus cells.Sterile Filtered colorless solution.KLRB1 has an inhibitory role on natural killer (NK) cells cytotoxicity which are lymphocytes who facilitate cytotoxicity and secrete cytokines subsequent to immune stimulation. Some genes of the C-type lectin superfamily, like the rodent NKRP1 family of glycoproteins, are expressed by NK cells and take part in NK cell function regulation. KLRB1 holds an extracellular domain with a few characteristic motifs of C-type lectins, a transmembrane domain, and a cytoplasmic domain. Due to its external C terminus KLRB1 is considered to be a type II membrane protein.KLRB1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 401 amino acids (67-225a.a.) and having a molecular mass of 45.7kDa. (Molecular size on SDS-PAGE will appear at approximately 40-57kDa) .KLRB1 is expressed with a 242 amino acid hIgG-His-tag at C-Terminus and purified by proprietary chromatographic techniques.