STK3 Human

Source: Sf9 Insect cells.Sterile Filtered colorless solution.Serine/threonine-protein kinase 3 (), is a mammalian Ste20-related protein kinases most closely related to Drosophila Hippo, which is a major regulator of cell proliferation as well as survival in the course of development. STK3 is a serine/threonine kinase which functions early in a pheromone responsive signal transduction cascade in yeast. Furthermore, STK3 activates the human large tumor suppressor kinase Lats1. STK3 also modulates stress-induced cardiac hypertrophy.STK3 Human Recombinant produced in Sf9 Insect cell is a single, non-glycosylated polypeptide chain containing 331 amino acids (1-322aa.a) and having a molecular mass of 37.6kDa (Migrates at 40-57kDa on SDS-PAGE under reducing conditions) .STK3 is fused to a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.