Human Interleukin-22

Source: Genetically modified E.coli. Predicted MW: Dimer, 16.9/33.8 kDa (147/294 aa) Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocytes. IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10RB chains. IL-22 is a potent mediator of cellular inflammatory responses.

Product Specifications

Product Name Alternative

Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL-TIF

Gene Name

IL22

Gene ID

50616

UniProt

Q9GZX6

Purification

Reducing and Non-Reducing SDS PAGE at >= 95%

Components

0.1mg/ ml from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium citrate, pH 3.0

Storage Conditions

Store at -20°C

Applications Notes

Endotoxin: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.

Amino Acids

MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI