Human Interleukin-22
Source: Genetically modified E.coli. Predicted MW: Dimer, 16.9/33.8 kDa (147/294 aa) Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocytes. IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10RB chains. IL-22 is a potent mediator of cellular inflammatory responses.
Product Specifications
Product Name Alternative
Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL-TIF
Gene Name
IL22
Gene ID
50616
UniProt
Q9GZX6
Purification
Reducing and Non-Reducing SDS PAGE at >= 95%
Components
0.1mg/ ml from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium citrate, pH 3.0
Shipping Conditions
Room temperature
Storage Conditions
Store at -20°C
Applications Notes
Endotoxin: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.
Amino Acids
MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI
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