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Spermine (N3BBB)

Spermine (N3BBB) is a click chemistry reagent containing an azide group and can be used for various biochemical studies[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

1190203-80-5

UNSPSC

12352211

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/spermine-n3bbb.html

Purity

98.04

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

[N-]=[N+]=NCCCN(CCCCN(CCCNC(OC(C)(C)C)=O)C(OC(C)(C)C)=O)C(OC(C)(C)C)=O

Molecular Formula

C25H48N6O6

Molecular Weight

528.69

References & Citations

[1]Roeland Vanhoutte, et al. Clickable Polyamine Derivatives as Chemical Probes for the Polyamine Transport System. Chembiochem. 2018 May 4;19 (9) :907-911.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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