Recombinant Human Activin Receptor-Like Kinase 1/ALK-1 (C-Fc)

Source : Human Cells; Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-Betasuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. The mutations of ALK-1 are associated with Rendu-Osler-Weber syndrome 2, this suggests ACVRL1 is associated with blood vessel development and repair