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Recombinant Human Beta-2 microglobulin/B2M (C-His)

Source : Human 293 Cells; Beta-2-microglobulin (B2M) is a component of MHC class I molecules that is a member of the beta-2-microglobulin family. B2M is present on all nucleated cells except for red blood cells. B2M can interact with HFE protein, together regulating the expression of hepcidin in the liver which targets the iron transporter ferroportin on the cytoplasmic membrane of enterocytes and macrophages for degradation, resulting in decreased iron uptake from food and iron release from recycled red blood cells respectively. Additionally, low levels of B2M can be the indicator for non-progression of HIV.

Product Specifications

Product Name Alternative

Beta-2-Microglobulin; B2M

Components

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2

Shipping Conditions

Ambient

Amino Acids

Recombinant Human Beta-2 microglobulin is produced by our Mammalian expression system and the target gene encoding Ile21-Met119 is expressed with a 6His tag at the C-terminus.
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