Drofenine (hydrochloride)
Drofenine (Cycloadiphene) hydrochloride is a potent competitive cholinesterase inhibitor with a Ki value of 3 μM[1].
Product Specifications
CAS Number
548-66-3
Product Name Alternative
Hexahydroadiphenine hydrochloride
UNSPSC
12352005
Hazard Statement
H302, H319, H372, H410
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Drofenine-hydrochloride.html
Purity
98.10
Solubility
DMSO : ≥ 75 mg/mL|H2O : ≥ 33.3 mg/mL
Smiles
O=C(OCCN(CC)CC)C(C1CCCCC1)C2=CC=CC=C2.[H]Cl
Molecular Formula
C20H32ClNO2
Molecular Weight
353.93
Precautions
H302, H319, H372, H410
References & Citations
[1]Bodur E, et al. Inhibition effects of benactyzine and drofenine on human serum butyrylcholinesterase. Arch Biochem Biophys. 2001 Feb 1;386 (1) :25-29.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
BChE
Available Sizes
Frequently Asked Questions
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