Recombinant Human Leukotriene A-4 Hydrolase/LTA4H (C-6His)

Source: Human Cells. MW :70.3kD. Recombinant Human Leukotriene A-4 hydrolase is produced by our Mammalian expression system and the target gene encoding Met1-Asp611 is expressed with a 6His tag at the C-terminus. LTA4H, which is short for Leukotriene A-4 hydrolase, is a 611 aa. protein. It belongs to the peptidase M1 family, and exists in cytoplasm. This protein has at least 4 isforms produced by alternative splicing, and two of them are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts. LTA4H involves in lipid metabolism and leukotriene B4 biosynthesis. It is a epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. It also has aminopeptidase activity