Recombinant Human Transaldolase/TALDO1 (C-6His)

Source: Human Cells. MW :38.5kD. Recombinant Human Transaldolase is produced by our Mammalian expression system and the target gene encoding Met1-Lys337 is expressed with a 6His tag at the C-terminus. Transaldolase (TALDO1) belongs to the transaldolase family of Type 1 subfamily. TALDO1 is expressed selectively in oligodendrocytes of the brain. TALDO1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. TALDO1 deficiency results in telangiectases of the skin, hepatosplenomegaly and enlarged clitoris.