Recombinant Mouse Granzyme B (G, H) /GZMB (C-6His)
Source: Human Cells. MW :26.5kD. Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus. Granzyme B (GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Product Specifications
Gene Name
Gzmb
Gene ID
14939
UniProt
P04187
Components
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Shipping Conditions
The product is shipped on dry ice/ice packs.
Storage Conditions
Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Applications Notes
Endotoxin : Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Amino Acids
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GOT2 (Glutamic-oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2), Aspartate Aminotransferase, Mitochondrial, FABP-1, FABPpm, Fatty Acid-binding Protein, FLJ40994, Glutamate Oxaloacetate Transaminase 2, KAT4, KATIV, mAspAT, mitAAT, P
GOT2 (Glutamic-oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2), Aspartate Aminotransferase, Mitochondrial, FABP-1, FABPpm, Fatty Acid-binding Protein, FLJ40994, Glutamate Oxaloacetate Transaminase 2, KAT4, KATIV, mAspAT, mitAAT, P
3-{5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}propan-1-ol
3-{5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}propan-1-ol
3-{5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}propan-1-ol