Recombinant Human Hydroxyacid Oxidase 1/HAO1 (N-Trx, 6His)

Source: E.coli. MW :58.6kD. Recombinant Human Hydroxyacid Oxidase 1 is produced by our E.coli expression system and the target gene encoding Met1-Ile370 is expressed with a Trx, 6His tag at the N-terminus. Hydroxyacid Oxidase 1 (HAO1) is an enzyme that belongs to the FMN-Dependent a-Hydroxy Acid Dehydrogenase family. HAO1 contains 1 FMN Hydroxy Ccid Dehydrogenase domain. HAO1 is expressed primarily in the liver and pancreas. This protein has 2-Hydroxyacid Oxidase activity. Most HAO1 is active on the 2-Carbon substrate Glycolate, but it can also be active on 2-Hydroxy fatty acids, with higher activity towards 2-Hydroxy Palmitate and 2-Hydroxy Octanoate.