IL1A Human, His Active
Source: E.coli.Sterile Filtered colorless solution.IL-1 alpha is derived fromactivated macrophages. IL1A proteins take part in the inflammatory response, being identified as endogenous pyrogens, and stimulate the release of prostaglandin and collagenase from synovial cells.IL-1 alpha stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity.IL1A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 197 amino acids (113-271 a.a) and having a molecular mass of 22.4kDa. IL1A is fused to a 38 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Specifications
Product Name Alternative
Applications
Functional Assay
Purification
Greater than 90% as determined by SDS-PAGE.
Components
IL1A protein solution (1mg/mL) contains 20mM Tris-HCl (pH 7.5) and 10% glycerol.
Storage Conditions
Applications Notes
Measured in a cell proliferation assay using D10.G4.1 mouse helper T cell. The ED50 for this effect is less or equal to 0.04 ng/ml.
Amino Acids
Frequently Asked Questions
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