SARS Spike Mosaic Protein
Source : The E.Coli derived 37 kDa recombinant mosaic protein contains the C-terminal t section of the Spike protein 1051-1076, 1121-1154, 1162-1190 amino acids immunodominant regions. SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S) -glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.
Product Specifications
Purification
SARS Mosaic Protein is >95% pure as determined by 10% PAGE (coomassie staining) .
Components
25mM Tris-HCl, 0.4% sarcosyl, 0.25% Triton -100 and 50% glycerol.
Storage Conditions
SARS Mosaic protein is shipped at ambient temperature.Upon arrival, store at -20C.
Applications Notes
SARS Mosaic antigen is suitable for ELISA and Western blots, excellent antigen for detection of SARS with minimal specificity problems
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