SARS Spike Mosaic S (N) Protein

Source : The E.Coli derived 38 kDa mosaic protein contains the N-terminal section of the Spike protein 12-53, 90-115, 171-203 amino acids immunodominant regions. SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S) -glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.

Product Specifications

Purification

SARS Mosaic Protein is >95% pure as determined by 10% PAGE (coomassie staining) .

Components

25mM Tris-HCl, 0.4% sarcosyl, 0.25% Triton -100 and 50% glycerol.

Storage Conditions

SARS Mosaic protein is shipped at ambient temperature. Upon arrival, store at -20C.

Applications Notes

SARS Mosaic protein is Immunoreactive with sera of SARS-infected individuals. SARS Mosaic antigen is suitable for ELISA and Western blots, excellent antigen for detection of SARS with minimal specificity problems.