Recombinant Human Y Box Binding Protein 1

Source : Escherichia Coli. YBX1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 347 amino acids (1-324a.a) and having a molecular mass of 38.3kDa. YBX1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Y Box Binding Protein 1 (YBX1) is a part of the CRD-mediated complex which promotes MYC mRNA stability. YBX1 takes part in mammalian selenoprotein translation and mediates pre-mRNA alternative splicing regulation. YBX1 uses as a drug target in cancer therapy due to its ability to replicate adenovirus type 5, a commonly used vector in gene therapy.

Product Specifications

Product Name Alternative

Y Box Binding Protein||NSEP1, DBPB||YB1||CCAAT-Binding Transcription Factor I Subunit A||Nuclease Sensitive Element Binding Protein||Enhancer Factor I Subunit A||Y-Box Transcription Factor||Y-Box-Binding Protein||DNA-Binding P||BP-8||CSDA2||CSDB||DBPB

Purification

Greater than 85.0% as determined by SDS-PAGE.

Components

YBX1 protein solution (0.5mg/mL) containing Phosphate Buffered Saline (pH7.4) and 20% glycerol.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Avoid multiple freeze-thaw cycles.

Amino Acids

MGSSHHHHHH SSGLVPRGSH MGSMSSEAET QQPPAAPPAA PALSAADTKP GTTGSGAGSG GPGGLTSAAP AGGDKKVIAT KVLGTVKWFN VRNGYGFINR NDTKEDVFVH QTAIKKNNPR KYLRSVGDGE TVEFDVVEGE KGAEAANVTG PGGVPVQGSK YAADRNHYRR YPRRRGPPRN YQQNYQNSES GEKNEGSESA PEGQAQQRRP YRRRRFPPYY MRRPYGRRPQ YSNPPVQGEV MEGADNQGAG EQGRPVRQNM YRGYRPRFRR GPPRQRQPRE DGNEEDKENQ GDETQGQQPP QRRYRRNFNY RRRRPENPKP QDGKETKAAD PPAENSSAPE AEQGGAE.