Recombinant Human Vesicle Transport Through Interaction with t-SNAREs Homolog 1B

Source : Escherichia Coli. VTI1B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 231 amino acids (1-208 a.a) and having a molecular mass of 26.3kDa (Molecular weight on SDS-PAGE will appear higher) .VTI1B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. VTI1B (v-SNARE) mediates vesicle transport pathways via interactions with t-SNAREs on the target membrane. These interactions are meant to facilitate aspects of the specificity of vesicle trafficking and to stimulate fusion of the lipid bilayers. VTI1B may be involved in increased secretion of cytokines connected with cellular senescence.