Recombinant Single Chain Cardiac Troponin I-C

Source : Escherichia Coli. Recombinant Single Chain Cardiac Troponin I-C produced in E.Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 45kDa.The scIC is purified by proprietary chromatographic techniques. Troponin Complex is a heteromeric protein playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, Troponin I, Troponin T and TroponinC. Each subunit is responsible for part of Troponin Complex function. E.g. Troponin I inhibits ATP-ase activity of acto-myosin.Troponin T and Troponin Iare presented in cardiac muscles in different forms than in skeletal muscles. Purified subunits of rcTnI, rcTnC and rcTnT are recomplexed in vitro under appropriate conditions.