Recombinant Human Tumor Protein P53 Regulated Apoptosis Inducing Protein 1

Source : Escherichia Coli. TP53AIP1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 144 amino acids (1-124) and having a molecular mass of 15kDa.TP53AIP1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Tumor Protein P53 Regulated Apoptosis Inducing Protein 1 (TP53AIP1) is expressed mainly in the thymus, and is localized to the mitochondrion. p53 induces TP53AIP1 production which then mediates p53- dependent apoptosis. Alternatively spliced transcript variants encoding diverse isoforms are known for TP53AIP1.

Product Specifications

Product Name Alternative

P53-regulated apoptosis-inducing protein 1||Tumor Protein P53 Regulated Apoptosis Inducing Protein 1||TP53AIP1||p53AIP1||P53-regulated apoptosis-inducing protein 1 isoform a||TPIP1||P53AIP1.

Purification

Greater than 85.0% as determined by SDS-PAGE.

Components

The TP53AIP1 solution (1mg/mL) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.

Amino Acids

MGSSHHHHHHSSGLVPRGSHMGSSSEASFR SAQASCSGAR RQGLGRGDQN LSVMPPNGRA QTHTPGWVSD PLVLGAQVHG GCRGIEALSV SSGSWSSATV WILTGLGLGL SRPFLPGATV LRDRPLGSAF ELSYDQKKAP LRLQ.