Recombinant Human Suppressor of Fused Homolog
Source : Escherichia Coli. SUFU Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 504 amino acids (1-484 a.a.) and having a molecular mass of 56.1kDa.SUFU is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Suppressor of fused homolog (SUFU) is a member of the SUFU family. SUFU is a negative regulator of the hedgehog signaling pathway. SUFU interacts with GLI1, GLI3 and PEX26. Defects in the SUFU gene are a cause of medulloblastoma.
Product Specifications
Product Name Alternative
Suppressor of fused homolog||SUFUH||SUFU||UNQ650/PRO1280||SUFUXL||PRO1280.
Purification
Greater than 90.0% as determined by SDS-PAGE.
Components
SUFU protein solution (0.5mg/mL) containing 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 10% glycerol and 50mM NaCl.
Storage Conditions
Amino Acids
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD54 / ICAM-1 (15.2), CF640R conjugate, 0.1mg/mL
