Recombinant Human STEAP Family Member 4

Source : Escherichia Coli. STEAP4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 188 amino acids (1-152 a.a) and having a molecular mass of 20.6kDa.STEAP4 is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. STEAP Family Member 4 (STEAP4) is a member of the STEAP (six transmembrane epithelial antigen of prostate) family, resides in the golgi apparatus. STEAP4 act as a metalloreductase which has the ability to reduce both Fe (3+) to Fe (2+) and Cu (2+) to Cu (1+), using NAD (+) as acceptor. According to studies in mice and human it is possible that STEAP4 may involve in adipocyte development and metabolism, and also contribute to the normal biology of the prostate cell.