Recombinant Human Serglycin, HEK

Source : HEK 293. Serglycin Human Recombinant produced in HEK cells is a single, glycosylated, polypeptide chain (Tyr28-Leu158) containing a total of 137 amino acids, having a calculated molecular mass of 15.5kDa and fused to a 6 aa His tag at C-Terminus. SRGN is identified as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells also hold a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is related to the macromolecular complex of granzymes and perforin that acts as a intermediary of granule-mediated apoptosis.

Product Specifications

Product Name Alternative

Serglycin||PRG||PRG1||PPG||Proteoglycan 1 secretory granule||Hematopoetic proteoglycan core protein||Platelet proteoglycan core protein||proteoglycan protein core for mast cell secretory granule.

Purification

Greater than 95.0% as determined by SDS-PAGE.

Components

SRGN filtered (0.4μm) solution at a concentration of 0.25mg/mL in phosphate buffered saline and 20% (w/v) glycerol.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.

Amino Acids

YPTRRARYQW VRCNPDSNSA NCLEEKGPMF ELLPGESNKI PRLRTDLFPK TRIQDLNRIF PLSEDYSGSG FGSGSGSGSG SGSGFLTEME QDYQLVDESD AFHDNLRSLD RNLPSDSQDL GQHGLEEDFM L HHHHHH.