Recombinant Human Speckle-Type POZ Protein
Source : Escherichia Coli. SPOP Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 394 amino acids (1-374 a.a.) and having a molecular mass of 44.3kDa. The SPOP is purified by proprietary chromatographic techniques. Speckle-type POZ protein (SPOP) belongs to the Tdpoz family containing one N-terminal MATH (Meprin and TRAF homology) domain and one C-terminal BTB/POZ domain. SPOP inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex. SPOP is involved in ubiquitinylation and protein degradation as a result of an interaction with CUL-3.
Product Specifications
Product Name Alternative
Speckle-type POZ protein||HIB homolog 1||Roadkill homolog 1||SPOP||TEF2.
Purification
Greater than 90.0% as determined by SDS-PAGE.
Components
The SPOP solution (0.5 mg/mL) contains 20mM Tris-HCl buffer (pH 8.0), 5mM DTT, 50% glycerol, 0.2M NaCl and 2mM EDTA.
Storage Conditions
Amino Acids
Frequently Asked Questions
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