Recombinant Human S100 Calcium Binding Protein A2

Source : Escherichia Coli. S100A2 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 117 amino acids (1-97 a.a.) and having a molecular mass of 13.1kDa. The S100A2 is purified by proprietary chromatographic techniques. S100A2 belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A2 may function as a modulator against excess calcium accumulation in normal human mammary epithelial cells and also have a role in suppressing tumor cell growth. S100A2 may have a tumor suppressor function. S100 family members are localized in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Chromosomal rearrangements and altered expression of the S100A2 gene are implicated in breast cancer.

Product Specifications

Product Name Alternative

Protein S100-A2||CAN19||Protein S-100L||S100 calcium-binding protein A2||S100A2||S100L||MGC111539.

Purification

Greater than 90.0% as determined by SDS-PAGE.

Components

The S100A2 solution (1 mg/mL) contains 20mM Tris-HCl buffer (pH 8.0), 5mM DTT, 30% glycerol and 0.2M NaCl.

Storage Conditions

S100A2 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.