Recombinant Human Ribosomal Protein S18

Source : Escherichia Coli. RPS18 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 175 amino acids (1-152 a.a) and having a molecular mass of 20.1kDa.RPS18 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. 40S ribosomal protein S18 (RPS18) is a member of the ribosomal protein S13P family. RPS18 is located in the cytoplasm. Ribosomes, the organelles which catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Jointly these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS18 encodes a ribosomal protein which is a component of the 40S subunit. RPS18 is a recognized binding partner of Cofilin and has been proposed to be a novel substrate for CaMKII. Among the diseases associated with RPS18 are bowen-conradi syndrome, and pasteurellosis.

Product Specifications

Product Name Alternative

Ribosomal Protein S18||D6S218E||40S Ribosomal Protein S18, HKE3||KE-3||KE3||S18||Rhabdomyosarcoma Antigen MU-RMS-40.21||Ke-3||Ke3.

Purification

Greater than 90.0% as determined by SDS-PAGE.

Components

RPS18 protein solution (0.5mg/mL) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.

Amino Acids

MGSSHHHHHH SSGLVPRGSH MGSMSLVIPE KFQHILRVLN TNIDGRRKIA FAITAIKGVG RRYAHVVLRK ADIDLTKRAG ELTEDEVERV ITIMQNPRQY KIPDWFLNRQ KDVKDGKYSQ VLANGLDNKL REDLERLKKI RAHRGLRHFW GLRVRGQHTK TTGRRGRTVG VSKKK