Recombinant Human Regulator of G-Protein Signaling 16

Source : Escherichia Coli. RGS16 Human Recombinant fused to 20 amino acid His Tag at N-terminal produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 222 amino acids (1-202 a.a.) and having a molecular mass of 24.9 kDa. The RGS16 is purified by proprietary chromatographic techniques. RGS16 is part of the ''regulator of G protein signaling'' family. RGS16 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. RGS16 Binds to G (i) -alpha and G (o) -alpha, but not to G (s) -alpha. RGS16 regulates the kinetics of signaling in the phototransduction cascade.

Product Specifications

Product Name Alternative

A28-RGS14||A28-RGS14P||RGS-R||Regulator of G-protein signaling 16||RGS16||Retinally abundant regulator of G-protein signaling||Retinal-specific RGS||hRGS-r||RGSR.

Purification

Greater than 90% as determined by SDS-PAGE.

Components

The RGS16 solution contains 20mM Tris-HCl pH-8, 0.1M NaCl and 20% glycerol.

Storage Conditions

RGS16 Recombinant Human although stable at 4°C for 30 days, should be stored desiccated below -20°C for periods greater than 30 days. Please avoid freeze-thaw cycles.

Amino Acids

MGSSHHHHHH SSGLVPRGSH MCRTLAAFPT TCLERAKEFK TRLGIFLHKS ELGCDTGSTG KFEWGSKHSK ENRNFSEDVL GWRESFDLLL SSKNGVAAFH AFLKTEFSEE NLEFWLACEE FKKIRSATKL ASRAHQIFEE FICSEAPKEV NIDHETRELT RMNLQTATAT CFDAAQGKTR TLMEKDSYPR FLKSPAYRDL AAQASAASAT LSSCSLDEPS HT.