Recombinant Human RAB5A, Member RAS Oncogene Family

Source : Escherichia Coli. RAB5A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 215 amino acids and having a molecular mass of 23kDa. RAB5A is a member of RAS oncogene family. The small GTPase, RAB5A is a crucial regulatory component of the endocytic pathway. Activation of RAB5A is mediated by GDP-GTP exchange factors (GEFs) that generate the Rab5-GTP complex) . RAB5A is required for the fusion of plasma membranes and early endosomes.

Product Specifications

Product Name Alternative

Ras-related protein Rab-5A||RAB5A||RAB5.

Purification

Greater than 95.0% as determined by SDS-PAGE.

Components

The protein solution contains 20mM Tris-HCl pH-8.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please prevent freeze-thaw cycles.

Amino Acids

MASRGATRPN GPNTGNKICQ FKLVLLGESA VGKSSLVLRF VKGQFHEFQE STIGAAFLTQTVCLDDTTVK FEIWDTAGQE RYHSLAPMYY RGAQAAIVVY DITNEESFAR AKNWVKELQRQASPNIVIAL SGNKADLANK RAVDFQEAQS YADDNSLLFM ETSAKTSMNV NEIFMAIAKKLPKNEPQNPG ANSARGRGVD LTEPTQPTRN QCCSN.