Recombinant Human Peptidase Inhibitor 3

Source : Escherichia Coli. PI3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 118 amino acids (23-117) and having a molecular mass of 12.0kDa.PI3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. PI3 is an elastase-specific protease inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster.

Product Specifications

Product Name Alternative

Peptidase Inhibitor 3 Skin-Derived||Skin-Derived Antileukoproteinase||Protease Inhibitor 3 Skin-Derived (SKALP) ||WAP Four-Disulfide Core Domain Protein 14||WAP Four-Disulfide Core Domain 14||Elastase-Specific Inhibitor||Protease Inhibitor WAP3||ESI||

Purification

Greater than 80% as determined by SDS-PAGE.

Components

The PI3 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 10% glycerol.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.