Recombinant Human Non-T-cell Activation Linker

Source : Escherichia Coli. NTAL Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 238 amino acids (27-243 a.a.) and having a molecular mass of 26.2 kDa. NTAL protein is fused to a 21 amino acid His tag at N-terminus and is purified by standard chromatography. NTAL participates in FCER1 (high affinity immunoglobulin epsilon receptor) -mediated signaling in mast cells. NTAL takes part in BCR (B-cell antigen receptor) -mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I) -mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

Product Specifications

Product Name Alternative

LAT2||Linker for Activation of T CellsFamily Member 2||HSPC046||LAB||WBSCR15||WBSCR5||WSCR5||Non-T-cell activation linker||Linker for activation of B-cells||Membrane-associated adapter molecule||Williams-Beuren syndrome chromosomal region 5 protein||

Purification

Greater than 80% as determined by SDS-PAGE.

Components

NTAL Human solution containing 20mM Trsi HCL pH-8, & 10% glycerol.

Storage Conditions

NTAL Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.

Amino Acids

MGSSHHHHHH SSGLVPRGSH MRCSRPGAKR SEKIYQQRSL REDQQSFTGS RTYSLVGQAW PGPLADMAPT RKDKLLQFYP SLEDPASSRY QNFSKGSRHG SEEAYIDPIA MEYYNWGRFS KPPEDDDANS YENVLICKQK TTETGAQQEG IGGLCRGDLS LSLALKTGPT SGLCPSASPE EDEESEDYQN SASIHQWRES RKVMGQLQRE ASPGPVGSPD EEDGEPDYVN GEVAATEA.