Recombinant Human Nipsnap Homolog 1

Source : Escherichia Coli. NIPSNAP1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 307 amino acids (1-284a.a) and having a molecular mass of 35.7kDa.NIPSNAP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Nipsnap Homolog 1 (NIPSNAP1) belongs to the NipSnap family. NIPSNAP1 may take part in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and it is localized to the inner mitochondrial membrane as well, where it may be involved in mitochondrial DNA maintenance. A pseudogene of NIPSNAP1 is located on the short arm of chromosome 17. Among the diseases associated with NIPSNAP1 are maple syrup urine disease, and phenylketonuria.

Product Specifications

Product Name Alternative

Nipsnap Homolog 1 (C. Elegans) ||4 Nitrophenylphosphatase Domain And Non-Neuronal SNAP25-Like 1||NIPSNAP||C. Elegans||Homolog||Protein NipSnap Homolog 1||NipSnap1.

Purification

Greater than 85% as determined by SDS-PAGE.

Components

NIPSNAP1 protein solution (0.5mg/mL) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please avoid freeze thaw cycles.

Amino Acids

MGSSHHHHHH SSGLVPRGSH MGSMAPRLCS ISVTARRLLG GPGPRAGDVA SAAAARFYSK DNEGSWFRSL FVHKVDPRKD AHSTLLSKKE TSNLYKIQFH NVKPEYLDAY NSLTEAVLPK LHLDEDYPCS LVGNWNTWYG EQDQAVHLWR FSGGYPALMD CMNKLKNNKE YLEFRRERSQMLLSRRNQLL LEFSFWNEPQ PRMGPNIYEL RTYKLKPGTM IEWGNNWARA IKYRQENQEA VGGFFSQIGE LYVVHHLWAY KDLQSREETR NAAWRKRGWD ENVYYTVPLV RHMESRIMIP LKISPLQ