Recombinant Human Kv Channel Interacting Protein 3

Source : Escherichia Coli. KCNIP3 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 276 amino acids (1-256 a.a.) and having a molecular mass of 31.4kDa. The KCNIP3 is purified by proprietary chromatographic techniques. KCNIP3 belongs to a family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. KCNIP family members are small calcium binding proteins containing EF-hand-like domains. KCNIP3 also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Mutations in the presenilin genes are implicated in Alzheimer's disease.