Recombinant Human Junctional Sarcoplasmic Reticulum Protein 1

Source : Escherichia Coli. JSRP1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 354 amino acids (1-331) and having a molecular mass of 38.0kDa.JSRP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. JSRP1 takes part in excitation-contraction connection at the sarcoplasmic reticulum. JSRP1 is able to cooperate with CACNA1S, CACNB1 and calsequestrin to assist in regulating calcium influx and efflux in skeletal muscle.

Product Specifications

Product Name Alternative

Junctional Sarcoplasmic Reticulum Protein 1||Homolog of Mouse Skeletal Muscle Sarcoplasmic Reticulum Protein JP-45||Junctional-Face Membrane Protein Of 45 KDa Homolog||JP45||2310032K21Rik||Skeletal Muscle Sarcoplasmic Reticulum Protein JP-45.

Purification

Greater than 90.0% as determined by SDS-PAGE.

Components

The JSRP1 solution (0.25mg/mL) contains 20mM Tris-HCl buffer (pH8.0), 0.15M NaCl and 10% glycerol.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.

Amino Acids

MGSSHHHHHH SSGLVPRGSH MGSMSMTTRA WEELDGGLGS CQALEDHSAL AETQEDRASA TPRLADSGSV PHDSQVAEGP SVDTRPKKME KEPAARGTPG TGKERLKAGA SPRSVPARKK AQTAPPLQPP PPPPALSEEL PWGDLSLNKC LVLASLVALL GSAFQLCRDA VPGEAALQAR VPEPWVPPSS APREPSSPLP KFEAQAPPSA PPAPRAEAEV RPKIPGSREA AENDEEEPGE ATGEAVREDR VTLADRGPKE RPRREGKPRK EKPRKEERPK KERPRKEERP RAAREPREAL PQRWESREGG HRPWARDSRD AEPRKKQAWV SPRRPDEEQR PGSRQKLRAG KGRD