2- ((Azido-PEG8-carbamoyl) methoxy) acetic acid
2- ((Azido-PEG8-carbamoyl) methoxy) acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 2- ((Azido-PEG8-carbamoyl) methoxy) acetic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[846549-37-9]
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-azido-peg8-carbamoyl-methoxy-acetic-acid.html
Purity
98.59
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O
Molecular Formula
C22H42N4O12
Molecular Weight
554.59
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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