EXOSC5 Recombinant Protein

Source : E.coli. EXOSC5 Human Recombinant produced in E. coli is a single polypeptide chain containing 256 amino acids (1-235) and having a molecular mass of 27.5kDa.EXOSC5 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. EXOSC5 is a member of the RNase PH family. EXOSC5 is known to cooperate with Exosome component 8 and Exosome component 1. EXOSC5 is a Non-catalytic component of the RNA exosome complex and has 3'->5' exoribonuclease activity. EXOSC5 take part in a large number of cellular RNA processing and degradation events. EXOSC5 is expressed in a large range of hematopoietic and epithelial tumor cell lines, but not in standard hematopoietic tissues or other standard tissue, with the exception of testis.