CREBZF Recombinant Protein

Source : Escherichia Coli. CREBZF Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 377 amino acids (1-354 a.a) and having a molecular mass of 39.5kDa. CREBZF is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. CREB/ATF BZIP Transcription Factor, also known as CREBZF activates transcription strongly once bound to HCFC1. CREBZF suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. CREBZF suppresses the HCFC1-dependent transcriptional activation through CREB3 and reduces the quantity of CREB3 in the cell. In addition, CREBZF is capable to down-regulate expression of a few cellular genes in CREBZF-expressing cells.

Product Specifications

Product Name Alternative

CREB/ATF BZIP Transcription Factor||Host Cell Factor-Binding Transcription Factor Zhangfei||HCF-Binding Transcription Factor Zhangfei||Zhangfei||ZF||SHP-Interacting Leucine Zipper Protein||SMILE||CREB/ATF bZIP transcription factor.

Purification

Greater than 85% as determined by SDS-PAGE.

Components

CREBZF protein solution (0.25mg/mL) containing PBS buffer (pH 7.4), 20% glycerol, 1mM DTT and 0.1mM PMSF.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.

Amino Acids

MGSSHHHHHH SSGLVPRGSH MGSMRHSLTK LLAASGSNSP TRSESPEPAA TCSLPSDLTR AAAGEEETAAAGSPGRKQQF GDEGELEAGR GSRGGVAVRA PSPEEMEEEA IASLPGEETE DMDFLSGLEL ADLLDPRQPDWHLDPGLSSP GPLSSSGGGS DSGGLWRGDD DDEAAAAEMQRFSDLLQRLL NGIGGCSSSS DSGSAEKRRR KSPGGGGGGG SGNDNNQAATKSPRKAAAAA ARLNRLKKKE YVMGLESRVR GLAAENQELR AENRELGKRV QALQEESRYL RAVLANETGLARLLSRLSGV GLRLTTSLFR DSPAGDHDYA LPVGKQKQDL LEEDDSAGGV CLHVDKDKVSVEFCSACARK ASSSLKM.